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Overexpression of CTHRC1 in Hepatocellular Carcinoma Promotes Tumor Invasion and Predicts Poor Prognosis

Collagen triple helix repeat containing-1 (CTHRC1) is a secreted glycoprotein that activates the planar cell polarity pathway of Wnt signaling. Using microarray analysis, we found that the CTHRC1 gene is overexpressed in hepatocellular carcinoma (HCC). The level of CTHRC1 mRNA was measured in 201 su...

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Detalles Bibliográficos
Autores principales: Chen, Yu-Ling, Wang, Ting-Huang, Hsu, Hey-Chi, Yuan, Ray-Hwang, Jeng, Yung-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3726622/
https://www.ncbi.nlm.nih.gov/pubmed/23922981
http://dx.doi.org/10.1371/journal.pone.0070324