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Crucial Role of TRPC1 and TRPC4 in Cystitis-Induced Neuronal Sprouting and Bladder Overactivity

PURPOSE: During cystitis, increased innervation of the bladder by sensory nerves may contribute to bladder overactivity and pain. The mechanisms whereby cystitis leads to hyperinnervation of the bladder are, however, poorly understood. Since TRP channels have been implicated in the guidance of growt...

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Detalles Bibliográficos
Autores principales: Boudes, Mathieu, Uvin, Pieter, Pinto, Silvia, Freichel, Marc, Birnbaumer, Lutz, Voets, Thomas, De Ridder, Dirk, Vennekens, Rudi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3726658/
https://www.ncbi.nlm.nih.gov/pubmed/23922735
http://dx.doi.org/10.1371/journal.pone.0069550