Alternative Immunomodulatory Strategies for Xenotransplantation: CD80/CD86-CTLA4 Pathway-Modified Immature Dendritic Cells Promote Xenograft Survival

BACKGROUND: Xenotransplantation is a promising approach to circumventing the current organ shortage. However, T-cell-dependent anti-xenoresponses are a major challenge to successful xenografts. Given the advantages of the use of CTLA4-Ig in the survival of allografts, the purpose of the study was to...

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Detalles Bibliográficos
Autores principales: Tian, Min, Lv, Yi, Zhai, Chao, Zhu, Haitao, Yu, Liang, Wang, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3726660/
https://www.ncbi.nlm.nih.gov/pubmed/23922766
http://dx.doi.org/10.1371/journal.pone.0069640

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3726660/
https://www.ncbi.nlm.nih.gov/pubmed/23922766
http://dx.doi.org/10.1371/journal.pone.0069640

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