Effect of Sequence and Stereochemistry Reversal on p53 Peptide Mimicry

Peptidomimetics effective in modulating protein-protein interactions and resistant to proteolysis have potential in therapeutic applications. An appealing yet underperforming peptidomimetic strategy is to employ D-amino acids and reversed sequences to mimic a lead peptide conformation, either separa...

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Detalles Bibliográficos
Autores principales: Atzori, Alessio, Baker, Audrey E., Chiu, Mark, Bryce, Richard A., Bonnet, Pascal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3726663/
https://www.ncbi.nlm.nih.gov/pubmed/23922660
http://dx.doi.org/10.1371/journal.pone.0068723

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3726663/
https://www.ncbi.nlm.nih.gov/pubmed/23922660
http://dx.doi.org/10.1371/journal.pone.0068723

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