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Effect of Sequence and Stereochemistry Reversal on p53 Peptide Mimicry
Peptidomimetics effective in modulating protein-protein interactions and resistant to proteolysis have potential in therapeutic applications. An appealing yet underperforming peptidomimetic strategy is to employ D-amino acids and reversed sequences to mimic a lead peptide conformation, either separa...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3726663/ https://www.ncbi.nlm.nih.gov/pubmed/23922660 http://dx.doi.org/10.1371/journal.pone.0068723 |