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Computational Study on the Different Ligands Induced Conformation Change of β2 Adrenergic Receptor-Gs Protein Complex

β(2) adrenergic receptor (β(2)AR) regulated many key physiological processes by activation of a heterotrimeric GTP binding protein (Gs protein). This process could be modulated by different types of ligands. But the details about this modulation process were still not depicted. Here, we performed mo...

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Detalles Bibliográficos
Autores principales: Bai, Qifeng, Zhang, Yang, Ban, Yihe, Liu, Huanxiang, Yao, Xiaojun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3726664/
https://www.ncbi.nlm.nih.gov/pubmed/23922653
http://dx.doi.org/10.1371/journal.pone.0068138