Induction of an Inflammatory Loop by Interleukin-1β and Tumor Necrosis Factor-α Involves NF-kB and STAT-1 in Differentiated Human Neuroprogenitor Cells

Proinflammatory cytokines secreted from microglia are known to induce a secondary immune response in astrocytes leading to an inflammatory loop. Cytokines also interfere with neurogenesis during aging and in neurodegenerative diseases. The present study examined the mechanism of induction of inflamm...

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Detalles Bibliográficos
Autores principales: Pugazhenthi, Subbiah, Zhang, Yuji, Bouchard, Ron, Mahaffey, Gregory
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3726669/
https://www.ncbi.nlm.nih.gov/pubmed/23922745
http://dx.doi.org/10.1371/journal.pone.0069585

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3726669/
https://www.ncbi.nlm.nih.gov/pubmed/23922745
http://dx.doi.org/10.1371/journal.pone.0069585

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