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Induction of an Inflammatory Loop by Interleukin-1β and Tumor Necrosis Factor-α Involves NF-kB and STAT-1 in Differentiated Human Neuroprogenitor Cells
Proinflammatory cytokines secreted from microglia are known to induce a secondary immune response in astrocytes leading to an inflammatory loop. Cytokines also interfere with neurogenesis during aging and in neurodegenerative diseases. The present study examined the mechanism of induction of inflamm...
Autores principales: | Pugazhenthi, Subbiah, Zhang, Yuji, Bouchard, Ron, Mahaffey, Gregory |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3726669/ https://www.ncbi.nlm.nih.gov/pubmed/23922745 http://dx.doi.org/10.1371/journal.pone.0069585 |
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