Optimizing Information in Next-Generation-Sequencing (NGS) Reads for Improving De Novo Genome Assembly

Next-Generation-Sequencing is advantageous because of its much higher data throughput and much lower cost compared with the traditional Sanger method. However, NGS reads are shorter than Sanger reads, making de novo genome assembly very challenging. Because genome assembly is essential for all downs...

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Detalles Bibliográficos
Autores principales: Liu, Tsunglin, Tsai, Cheng-Hung, Lee, Wen-Bin, Chiang, Jung-Hsien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3726674/
https://www.ncbi.nlm.nih.gov/pubmed/23922726
http://dx.doi.org/10.1371/journal.pone.0069503

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3726674/
https://www.ncbi.nlm.nih.gov/pubmed/23922726
http://dx.doi.org/10.1371/journal.pone.0069503

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