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Optimizing Information in Next-Generation-Sequencing (NGS) Reads for Improving De Novo Genome Assembly
Next-Generation-Sequencing is advantageous because of its much higher data throughput and much lower cost compared with the traditional Sanger method. However, NGS reads are shorter than Sanger reads, making de novo genome assembly very challenging. Because genome assembly is essential for all downs...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3726674/ https://www.ncbi.nlm.nih.gov/pubmed/23922726 http://dx.doi.org/10.1371/journal.pone.0069503 |