Autophagy Activation Clears ELAVL1/HuR-Mediated Accumulation of SQSTM1/p62 during Proteasomal Inhibition in Human Retinal Pigment Epithelial Cells

Age-related macular degeneration (AMD) is the most common reason of visual impairment in the elderly in the Western countries. The degeneration of retinal pigment epithelial cells (RPE) causes secondarily adverse effects on neural retina leading to visual loss. The aging characteristics of the RPE i...

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Detalles Bibliográficos
Autores principales: Viiri, Johanna, Amadio, Marialaura, Marchesi, Nicoletta, Hyttinen, Juha M. T., Kivinen, Niko, Sironen, Reijo, Rilla, Kirsi, Akhtar, Saeed, Provenzani, Alessandro, D'Agostino, Vito Giuseppe, Govoni, Stefano, Pascale, Alessia, Agostini, Hansjurgen, Petrovski, Goran, Salminen, Antero, Kaarniranta, Kai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3726683/
https://www.ncbi.nlm.nih.gov/pubmed/23922739
http://dx.doi.org/10.1371/journal.pone.0069563

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3726683/
https://www.ncbi.nlm.nih.gov/pubmed/23922739
http://dx.doi.org/10.1371/journal.pone.0069563

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