CBP Activity Mediates Effects of the Histone Deacetylase Inhibitor Butyrate on WNT Activity and Apoptosis in Colon Cancer Cells

Mutations in the WNT/beta-catenin pathway are responsible for initiating the majority of colorectal cancers (CRCs). We have previously shown that hyperactivation of this signaling by histone deacetylase inhibitors (HDACis) such as butyrate, a fermentation product of dietary fiber, promotes CRC cell...

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Detalles Bibliográficos
Autores principales: Lazarova, Darina L, Chiaro, Christopher, Wong, Terrence, Drago, Eric, Rainey, Anthony, O'Malley, Shannon, Bordonaro, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2013
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3726710/
https://www.ncbi.nlm.nih.gov/pubmed/23901348
http://dx.doi.org/10.7150/jca.6583

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3726710/
https://www.ncbi.nlm.nih.gov/pubmed/23901348
http://dx.doi.org/10.7150/jca.6583

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