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p300 Influences Butyrate-Mediated WNT Hyperactivation In Colorectal Cancer Cells

Deregulated WNT/catenin pathway, usually resulting from mutations in the adenomatous polyposis coli and beta-catenin genes, drives colorectal tumorigenesis. Dietary fiber has been shown to have a protective role against colorectal cancer (CRC). We have previously demonstrated that the histone deacet...

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Detalles Bibliográficos
Autores principales: Lazarova, Darina L, Wong, Terrence, Chiaro, Christopher, Drago, Eric, Bordonaro, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3726711/
https://www.ncbi.nlm.nih.gov/pubmed/23901349
http://dx.doi.org/10.7150/jca.6582