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Notch1 Signaling Regulates the Proliferation and Self-Renewal of Human Dental Follicle Cells by Modulating the G1/S Phase Transition and Telomerase Activity

Multipotent human dental follicle cells (HDFCs) have been intensively studied in periodontal regeneration research, yet the role of Notch1 in HDFCs has not been fully understood. The aim of the current study is to explore the role of Notch1 signaling in HDFCs self-renewal and proliferation. HDFCs we...

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Detalles Bibliográficos
Autores principales: Chen, Xuepeng, Zhang, Tianhou, Shi, Jiejun, Xu, Ping, Gu, Zexu, Sandham, Andrew, Yang, Lei, Ye, Qingsong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3726724/
https://www.ncbi.nlm.nih.gov/pubmed/23922876
http://dx.doi.org/10.1371/journal.pone.0069967