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Schiff Base Switch II Precedes the Retinal Thermal Isomerization in the Photocycle of Bacteriorhodopsin

In bacteriorhodopsin, the order of molecular events that control the cytoplasmic or extracellular accessibility of the Schiff bases (SB) are not well understood. We use molecular dynamics simulations to study a process involved in the second accessibility switch of SB that occurs after its reprotona...

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Detalles Bibliográficos
Autores principales: Wang, Ting, Facciotti, Marc T., Duan, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3726731/
https://www.ncbi.nlm.nih.gov/pubmed/23922839
http://dx.doi.org/10.1371/journal.pone.0069882