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Morphoproteomic Profiling of the Mammalian Target of Rapamycin (mTOR) Signaling Pathway in Desmoplastic Small Round Cell Tumor (EWS/WT1), Ewing’s Sarcoma (EWS/FLI1) and Wilms’ Tumor(WT1)

BACKGROUND: Desmoplastic small round cell tumor (DSRCT) is a rare sarcoma in adolescents and young adults. The hallmark of this disease is a EWS-WT1 translocation resulting from apposition of the Ewing’s sarcoma (EWS) gene with the Wilms’ tumor (WT1) gene. We performed morphoproteomic profiling of D...

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Detalles Bibliográficos
Autores principales: Subbiah, Vivek, Brown, Robert E., Jiang, Yunyun, Buryanek, Jamie, Hayes-Jordan, Andrea, Kurzrock, Razelle, Anderson, Pete M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3726753/
https://www.ncbi.nlm.nih.gov/pubmed/23922674
http://dx.doi.org/10.1371/journal.pone.0068985