Differential Programming of B Cells in AID Deficient Mice

The Aicda locus encodes the activation induced cytidine deaminase (AID) and is highly expressed in germinal center (GC) B cells to initiate somatic hypermutation (SHM) and class switch recombination (CSR) of immunoglobulin (Ig) genes. Besides these Ig specific activities in B cells, AID has been imp...

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Detalles Bibliográficos
Autores principales: Hogenbirk, Marc A., Heideman, Marinus R., Velds, Arno, van den Berk, Paul CM., Kerkhoven, Ron M., van Steensel, Bas, Jacobs, Heinz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3726761/
https://www.ncbi.nlm.nih.gov/pubmed/23922811
http://dx.doi.org/10.1371/journal.pone.0069815

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3726761/
https://www.ncbi.nlm.nih.gov/pubmed/23922811
http://dx.doi.org/10.1371/journal.pone.0069815

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