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Macromolecular Crowding as a Suppressor of Human IAPP Fibril Formation and Cytotoxicity
The biological cell is known to exhibit a highly crowded milieu, which significantly influences protein aggregation and association processes. As several cell degenerative diseases are related to the self-association and fibrillation of amyloidogenic peptides, understanding of the impact of macromol...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3726762/ https://www.ncbi.nlm.nih.gov/pubmed/23922768 http://dx.doi.org/10.1371/journal.pone.0069652 |