Modulation of the Akt Pathway Reveals a Novel Link with PERK/eIF2α, which Is Relevant during Hypoxia

The unfolded protein response (UPR) and the Akt signaling pathway share several regulatory functions and have the capacity to determine cell outcome under specific conditions. However, both pathways have largely been studied independently. Here, we asked whether the Akt pathway regulates the UPR. To...

Descripción completa

Detalles Bibliográficos
Autores principales: Blaustein, Matías, Pérez-Munizaga, Daniela, Sánchez, Manuel Alejandro, Urrutia, Carolina, Grande, Alicia, Risso, Guillermo, Srebrow, Anabella, Alfaro, Jennifer, Colman-Lerner, Alejandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3726764/
https://www.ncbi.nlm.nih.gov/pubmed/23922774
http://dx.doi.org/10.1371/journal.pone.0069668

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3726764/
https://www.ncbi.nlm.nih.gov/pubmed/23922774
http://dx.doi.org/10.1371/journal.pone.0069668

Ejemplares similares