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From Interaction to Co-Association —A Fisher r-To-z Transformation-Based Simple Statistic for Real World Genome-Wide Association Study

Currently, the genetic variants identified by genome wide association study (GWAS) generally only account for a small proportion of the total heritability for complex disease. One crucial reason is the underutilization of gene-gene joint effects commonly encountered in GWAS, which includes their mai...

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Detalles Bibliográficos
Autores principales: Yuan, Zhongshang, Liu, Hong, Zhang, Xiaoshuai, Li, Fangyu, Zhao, Jinghua, Zhang, Furen, Xue, Fuzhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3726765/
https://www.ncbi.nlm.nih.gov/pubmed/23923021
http://dx.doi.org/10.1371/journal.pone.0070774