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Histone Demethylase Retinoblastoma Binding Protein 2 is Overexpressed in Hepatocellular Carcinoma and Negatively Regulated by hsa-miR-212

BACKGROUND: The H3K4 demethylase retinoblastoma binding protein 2 (RBP2) is involved in the pathogenesis of gastric cancer, but its role and regulation in hepatocellular carcinoma (HCC) is unknown. We determined the function of RBP2 and its regulation in HCC in vitro and in human tissues. METHODS: W...

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Detalles Bibliográficos
Autores principales: Liang, Xiuming, Zeng, Jiping, Wang, Lixiang, Fang, Ming, Wang, Qing, Zhao, Min, Xu, Xia, Liu, Zhifang, Li, Wenjuan, Liu, Shili, Yu, Han, Jia, Jihui, Chen, Chunyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3726779/
https://www.ncbi.nlm.nih.gov/pubmed/23922798
http://dx.doi.org/10.1371/journal.pone.0069784