Importance of the Difference in Surface Pressures of the Cell Membrane in Doxorubicin Resistant Cells That do not Express Pgp and ABCG2

P-glycoprotein (Pgp) represents the archetypal mechanism of drug resistance. But Pgp alone cannot expel drugs. A small but growing body of works has demonstrated that the membrane biophysical properties are central to Pgp-mediated drug resistance. For example, a change in the membrane surface pressu...

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Detalles Bibliográficos
Autores principales: Bell, Charlotte, Hill, Claire, Burton, Christopher, Blanchard, Adam, Shephard, Freya, Rauch, Cyril
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2013
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3726932/
https://www.ncbi.nlm.nih.gov/pubmed/23314884
http://dx.doi.org/10.1007/s12013-012-9497-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3726932/
https://www.ncbi.nlm.nih.gov/pubmed/23314884
http://dx.doi.org/10.1007/s12013-012-9497-0

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