The G-protein–gated K(+) channel, I(KACh), is required for regulation of pacemaker activity and recovery of resting heart rate after sympathetic stimulation

Parasympathetic regulation of sinoatrial node (SAN) pacemaker activity modulates multiple ion channels to temper heart rate. The functional role of the G-protein–activated K(+) current (I(KACh)) in the control of SAN pacemaking and heart rate is not completely understood. We have investigated the fu...

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Detalles Bibliográficos
Autores principales: Mesirca, Pietro, Marger, Laurine, Toyoda, Futoshi, Rizzetto, Riccardo, Audoubert, Matthieu, Dubel, Stefan, Torrente, Angelo G., DiFrancesco, Mattia L., Muller, Jana Christina, Leoni, Anne-Laure, Couette, Brigitte, Nargeot, Joël, Clapham, David E., Wickman, Kevin, Mangoni, Matteo E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2013
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3727310/
https://www.ncbi.nlm.nih.gov/pubmed/23858001
http://dx.doi.org/10.1085/jgp.201310996

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3727310/
https://www.ncbi.nlm.nih.gov/pubmed/23858001
http://dx.doi.org/10.1085/jgp.201310996

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