Immune history shapes specificity of pandemic H1N1 influenza antibody responses

Human antibody responses against the 2009 pandemic H1N1 (pH1N1) virus are predominantly directed against conserved epitopes in the stalk and receptor-binding domain of the hemagglutinin (HA) protein. This is in stark contrast to pH1N1 antibody responses generated in ferrets, which are focused on the...

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Detalles Bibliográficos
Autores principales: Li, Yang, Myers, Jaclyn L., Bostick, David L., Sullivan, Colleen B., Madara, Jonathan, Linderman, Susanne L., Liu, Qin, Carter, Donald M., Wrammert, Jens, Esposito, Susanna, Principi, Nicola, Plotkin, Joshua B., Ross, Ted M., Ahmed, Rafi, Wilson, Patrick C., Hensley, Scott E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2013
Materias:
Brief Definitive Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3727314/
https://www.ncbi.nlm.nih.gov/pubmed/23857983
http://dx.doi.org/10.1084/jem.20130212

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3727314/
https://www.ncbi.nlm.nih.gov/pubmed/23857983
http://dx.doi.org/10.1084/jem.20130212

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