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Immune history shapes specificity of pandemic H1N1 influenza antibody responses
Human antibody responses against the 2009 pandemic H1N1 (pH1N1) virus are predominantly directed against conserved epitopes in the stalk and receptor-binding domain of the hemagglutinin (HA) protein. This is in stark contrast to pH1N1 antibody responses generated in ferrets, which are focused on the...
Autores principales: | Li, Yang, Myers, Jaclyn L., Bostick, David L., Sullivan, Colleen B., Madara, Jonathan, Linderman, Susanne L., Liu, Qin, Carter, Donald M., Wrammert, Jens, Esposito, Susanna, Principi, Nicola, Plotkin, Joshua B., Ross, Ted M., Ahmed, Rafi, Wilson, Patrick C., Hensley, Scott E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3727314/ https://www.ncbi.nlm.nih.gov/pubmed/23857983 http://dx.doi.org/10.1084/jem.20130212 |
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