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MK5 activates Rag transcription via Foxo1 in developing B cells

Foxo1 is a critical, direct regulator of Rag (recombination activating gene) transcription during B cell development and is thus essential for the generation of a diverse repertoire of antigen receptors. Although Foxo1 regulation has been widely studied in many cell types, pathways regulating Foxo1...

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Detalles Bibliográficos
Autores principales: Chow, Kwan T., Timblin, Greg A., McWhirter, Sarah M., Schlissel, Mark S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3727319/
https://www.ncbi.nlm.nih.gov/pubmed/23878308
http://dx.doi.org/10.1084/jem.20130498