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CD4(+) T helper cells use CD154–CD40 interactions to counteract T reg cell–mediated suppression of CD8(+) T cell responses to influenza
CD4(+) T cells promote CD8(+) T cell priming by licensing dendritic cells (DCs) via CD40–CD154 interactions. However, the initial requirement for CD40 signaling may be replaced by the direct activation of DCs by pathogen-derived signals. Nevertheless, CD40–CD154 interactions are often required for o...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3727323/ https://www.ncbi.nlm.nih.gov/pubmed/23835849 http://dx.doi.org/10.1084/jem.20130097 |