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Tumor cell entry into the lymph node is controlled by CCL1 chemokine expressed by lymph node lymphatic sinuses

Lymphatic vessels are thought to contribute to metastasis primarily by serving as a transportation system. It is widely believed that tumor cells enter lymph nodes passively by the flow of lymph. We demonstrate that lymph node lymphatic sinuses control tumor cell entry into the lymph node, which req...

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Detalles Bibliográficos
Autores principales: Das, Suvendu, Sarrou, Eliana, Podgrabinska, Simona, Cassella, Melanie, Mungamuri, Sathish Kumar, Feirt, Nikki, Gordon, Ronald, Nagi, Chandandeep S., Wang, Yarong, Entenberg, David, Condeelis, John, Skobe, Mihaela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3727324/
https://www.ncbi.nlm.nih.gov/pubmed/23878309
http://dx.doi.org/10.1084/jem.20111627