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The yeast dynein Dyn2-Pac11 complex is a dynein dimerization/processivity factor: structural and single-molecule characterization

Cytoplasmic dynein is the major microtubule minus end–directed motor. Although studies have probed the mechanism of the C-terminal motor domain, if and how dynein's N-terminal tail and the accessory chains it binds regulate motor activity remain to be determined. Here, we investigate the struct...

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Detalles Bibliográficos
Autores principales: Rao, Lu, Romes, Erin M., Nicholas, Matthew P., Brenner, Sibylle, Tripathy, Ashutosh, Gennerich, Arne, Slep, Kevin C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3727929/
https://www.ncbi.nlm.nih.gov/pubmed/23761070
http://dx.doi.org/10.1091/mbc.E13-03-0166