Selective constraint, background selection, and mutation accumulation variability within and between human populations

BACKGROUND: Regions of the genome that are under evolutionary constraint across multiple species have previously been used to identify functional sequences in the human genome. Furthermore, it is known that there is an inverse relationship between evolutionary constraint and the allele frequency of...

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Detalles Bibliográficos
Autores principales: Hodgkinson, Alan, Casals, Ferran, Idaghdour, Youssef, Grenier, Jean-Christophe, Hernandez, Ryan D, Awadalla, Philip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3727949/
https://www.ncbi.nlm.nih.gov/pubmed/23875710
http://dx.doi.org/10.1186/1471-2164-14-495

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3727949/
https://www.ncbi.nlm.nih.gov/pubmed/23875710
http://dx.doi.org/10.1186/1471-2164-14-495

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