NF-kB overexpression and decreased immunoexpression of AR in the muscular layer is related to structural damages and apoptosis in cimetidine-treated rat vas deferens

BACKGROUND: Cimetidine, histamine H(2) receptors antagonist, has caused adverse effects on the male hormones and reproductive tract due to its antiandrogenic effect. In the testes, peritubular myoid cells and muscle vascular cells death has been associated to seminiferous tubules and testicular micr...

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Detalles Bibliográficos
Autores principales: Koshimizu, Juliana Y, Beltrame, Flávia L, de Pizzol, José P, Cerri, Paulo S, Caneguim, Breno H, Sasso-Cerri, Estela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3727959/
https://www.ncbi.nlm.nih.gov/pubmed/23570504
http://dx.doi.org/10.1186/1477-7827-11-29

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3727959/
https://www.ncbi.nlm.nih.gov/pubmed/23570504
http://dx.doi.org/10.1186/1477-7827-11-29

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