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Transcription factor NFκB regulates the expression of the histone deacetylase SIRT1

BACKGROUND: The NAD-dependent protein deacetylase SIRT1 has a wide range of different targets, which may be regulated either directly through deacetylation and thus potentially altering their activity or localization or indirectly by deacetylation of histones, which in turn alters their transcriptio...

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Detalles Bibliográficos
Autores principales: Katto, Judith, Engel, Nicole, Abbas, Wasim, Herbein, Georges, Mahlknecht, Ulrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3727996/
https://www.ncbi.nlm.nih.gov/pubmed/23870485
http://dx.doi.org/10.1186/1868-7083-5-11