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NOTCH1 Gain of Function in Germ Cells Causes Failure of Spermatogenesis in Male Mice

NOTCH1 is a member of the NOTCH receptor family, a group of single-pass trans-membrane receptors. NOTCH signaling is highly conserved in evolution and mediates communication between adjacent cells. NOTCH receptors have been implicated in cell fate determination, as well as maintenance and differenti...

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Detalles Bibliográficos
Autores principales: Huang, Zaohua, Rivas, Bryan, Agoulnik, Alexander I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3728026/
https://www.ncbi.nlm.nih.gov/pubmed/23936265
http://dx.doi.org/10.1371/journal.pone.0071213