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Induction of Premalignant Host Responses by Cathepsin X/Z-Deficiency in Helicobacter Pylori-Infected Mice

Helicobacter pylori are responsible for the induction of chronic gastric inflammation progressing to atrophy, metaplasia, and gastric cancer. The overexpression of Cathepsin X/Z (Ctsz) in H. pylori-infected mucosa and gastric cancer is mediated predominantly by an augmented migration of ctsz(−/−)pos...

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Detalles Bibliográficos
Autores principales: Krueger, Sabine, Bernhardt, Anja, Kalinski, Thomas, Baldensperger, Martin, Zeh, Michael, Teller, Anne, Adolf, Daniela, Reinheckel, Thomas, Roessner, Albert, Kuester, Doerthe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3728094/
https://www.ncbi.nlm.nih.gov/pubmed/23936173
http://dx.doi.org/10.1371/journal.pone.0070242