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Osteopontin genetic variants are associated with overall survival in advanced non-small-cell lung cancer patients and bone metastasis

PURPOSE: Osteopontin (OPN) plays important roles in the modulation of apoptosis, angiogenesis, immune response, and tumor invasion. Elevated osteopontin expression has been reported in the lung cancer tissues compared to counterpart normal tissues. This study examined whether genetic variations in t...

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Detalles Bibliográficos
Autores principales: Chen, Yunzhen, Liu, Haichun, Wu, Wenliang, Li, Yi, Li, Jianmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3728114/
https://www.ncbi.nlm.nih.gov/pubmed/23883434
http://dx.doi.org/10.1186/1756-9966-32-45