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Recent advances in recombinant protein production: BAC-based expression vectors, the bigger the better

Designing appropriate expression vectors is one of the critical steps in the generation of stable cell lines for recombinant protein production. Conventional expression vectors are severely affected by the chromatin environment surrounding their integration site into the host genome, resulting in lo...

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Detalles Bibliográficos
Autores principales: Kunert, Renate, Casanova, Emilio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3728198/
https://www.ncbi.nlm.nih.gov/pubmed/23680894
http://dx.doi.org/10.4161/bioe.24060