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Recent advances in recombinant protein production: BAC-based expression vectors, the bigger the better
Designing appropriate expression vectors is one of the critical steps in the generation of stable cell lines for recombinant protein production. Conventional expression vectors are severely affected by the chromatin environment surrounding their integration site into the host genome, resulting in lo...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Landes Bioscience
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3728198/ https://www.ncbi.nlm.nih.gov/pubmed/23680894 http://dx.doi.org/10.4161/bioe.24060 |