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Herbal compound triptolide synergistically enhanced antitumor activity of amino-terminal fragment of urokinase
BACKGROUND: Urokinase (uPA) and its receptor (uPAR) play an important role in tumour growth and metastasis, and overexpression of these molecules is strongly correlated with poor prognosis in a variety of malignant tumours. Targeting the excessive activation of this system as well as the proliferati...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3728221/ https://www.ncbi.nlm.nih.gov/pubmed/23758884 http://dx.doi.org/10.1186/1476-4598-12-54 |