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Generation of a tumor- and tissue-specific episomal non-viral vector system

BACKGROUND: A key issue for safe and reproducible gene therapy approaches is the autologous and tissue-specific expression of transgenes. Tissue-specific expression in vivo is either achieved by transfer vectors that deliver the gene of interest into a distinct cell type or by use of tissue-specific...

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Detalles Bibliográficos
Autores principales: Haase, Rudolf, Magnusson, Terese, Su, Baowei, Kopp, Florian, Wagner, Ernst, Lipps, Hans, Baiker, Armin, Ogris, Manfred
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3728224/
https://www.ncbi.nlm.nih.gov/pubmed/23734827
http://dx.doi.org/10.1186/1472-6750-13-49