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Spatiotemporal mathematical modelling of mutations of the dhps gene in African Plasmodium falciparum

BACKGROUND: Plasmodium falciparum has repeatedly evolved resistance to first-line anti-malarial drugs, thwarting efforts to control and eliminate the disease and in some period of time this contributed largely to an increase in mortality. Here a mathematical model was developed to map the spatiotemp...

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Detalles Bibliográficos
Autores principales: Flegg, Jennifer A, Patil, Anand P, Venkatesan, Meera, Roper, Cally, Naidoo, Inbarani, Hay, Simon I, Sibley, Carol Hopkins, Guerin, Philippe J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3728261/
https://www.ncbi.nlm.nih.gov/pubmed/23866695
http://dx.doi.org/10.1186/1475-2875-12-249