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Spatiotemporal mathematical modelling of mutations of the dhps gene in African Plasmodium falciparum
BACKGROUND: Plasmodium falciparum has repeatedly evolved resistance to first-line anti-malarial drugs, thwarting efforts to control and eliminate the disease and in some period of time this contributed largely to an increase in mortality. Here a mathematical model was developed to map the spatiotemp...
Autores principales: | Flegg, Jennifer A, Patil, Anand P, Venkatesan, Meera, Roper, Cally, Naidoo, Inbarani, Hay, Simon I, Sibley, Carol Hopkins, Guerin, Philippe J |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3728261/ https://www.ncbi.nlm.nih.gov/pubmed/23866695 http://dx.doi.org/10.1186/1475-2875-12-249 |
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