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Reconstruction of Cellular Signal Transduction Networks Using Perturbation Assays and Linear Programming
Perturbation experiments for example using RNA interference (RNAi) offer an attractive way to elucidate gene function in a high throughput fashion. The placement of hit genes in their functional context and the inference of underlying networks from such data, however, are challenging tasks. One of t...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3728289/ https://www.ncbi.nlm.nih.gov/pubmed/23935958 http://dx.doi.org/10.1371/journal.pone.0069220 |