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Activation of AMPK Inhibits Cholera Toxin Stimulated Chloride Secretion in Human and Murine Intestine

Increased intestinal chloride secretion through chloride channels, such as the cystic fibrosis transmembrane conductance regulator (CFTR), is one of the major molecular mechanisms underlying enterotoxigenic diarrhea. It has been demonstrated in the past that the intracellular energy sensing kinase,...

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Detalles Bibliográficos
Autores principales: Rogers, Ailín C., Huetter, Lisa, Hoekstra, Nadia, Collins, Danielle, Collaco, Anne, Baird, Alan W., Winter, Desmond C., Ameen, Nadia, Geibel, John P., Kopic, Sascha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3728293/
https://www.ncbi.nlm.nih.gov/pubmed/23935921
http://dx.doi.org/10.1371/journal.pone.0069050