Transcriptional Profiling of mRNAs and microRNAs in Human Bone Marrow Precursor B Cells Identifies Subset- and Age-Specific Variations

BACKGROUND: Molecular mechanisms explaining age-related changes in the bone marrow with reduced precursor B cell output are poorly understood. METHODS: We studied the transcriptome of five precursor B cell subsets in individual bone marrow samples from 4 healthy children and 4 adults employing GeneC...

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Detalles Bibliográficos
Autores principales: Jensen, Kristin, Brusletto, Berit Sletbakk, Aass, Hans Christian Dalsbotten, Olstad, Ole K., Kierulf, Peter, Gautvik, Kaare M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3728296/
https://www.ncbi.nlm.nih.gov/pubmed/23936243
http://dx.doi.org/10.1371/journal.pone.0070721

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3728296/
https://www.ncbi.nlm.nih.gov/pubmed/23936243
http://dx.doi.org/10.1371/journal.pone.0070721

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