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Transcriptional Profiling of mRNAs and microRNAs in Human Bone Marrow Precursor B Cells Identifies Subset- and Age-Specific Variations
BACKGROUND: Molecular mechanisms explaining age-related changes in the bone marrow with reduced precursor B cell output are poorly understood. METHODS: We studied the transcriptome of five precursor B cell subsets in individual bone marrow samples from 4 healthy children and 4 adults employing GeneC...
Autores principales: | Jensen, Kristin, Brusletto, Berit Sletbakk, Aass, Hans Christian Dalsbotten, Olstad, Ole K., Kierulf, Peter, Gautvik, Kaare M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3728296/ https://www.ncbi.nlm.nih.gov/pubmed/23936243 http://dx.doi.org/10.1371/journal.pone.0070721 |
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