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Assumptions and Properties of Limiting Pathway Models for Analysis of Epistasis in Complex Traits
For most complex traits, results from genome-wide association studies show that the proportion of the phenotypic variance attributable to the additive effects of individual SNPs, that is, the heritability explained by the SNPs, is substantially less than the estimate of heritability obtained by stan...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3728313/ https://www.ncbi.nlm.nih.gov/pubmed/23935903 http://dx.doi.org/10.1371/journal.pone.0068913 |