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Lentiviral Vector Mediated Thymidine Kinase Expression in Pluripotent Stem Cells Enables Removal of Tumorigenic Cells

Embryonic stem cells (ES) and induced pluripotent stem (iPS) cells represent promising tools for cell-based therapies and regenerative medicine. Nevertheless, implantation of ES cell derived differentiated cells holds the risk of teratoma formation due to residual undifferentiated cells. In order to...

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Detalles Bibliográficos
Autores principales: Lim, Tiong-Ti, Geisen, Caroline, Hesse, Michael, Fleischmann, Bernd K., Zimmermann, Katrin, Pfeifer, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3728319/
https://www.ncbi.nlm.nih.gov/pubmed/23936225
http://dx.doi.org/10.1371/journal.pone.0070543