Compound A, a Selective Glucocorticoid Receptor Modulator, Enhances Heat Shock Protein Hsp70 Gene Promoter Activation

Compound A possesses glucocorticoid receptor (GR)-dependent anti-inflammatory properties. Just like classical GR ligands, Compound A can repress NF-κB-mediated gene expression. However, the monomeric Compound A-activated GR is unable to trigger glucocorticoid response element-regulated gene expressi...

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Detalles Bibliográficos
Autores principales: Beck, Ilse M., Drebert, Zuzanna J., Hoya-Arias, Ruben, Bahar, Ali A., Devos, Michael, Clarisse, Dorien, Desmet, Sofie, Bougarne, Nadia, Ruttens, Bart, Gossye, Valerie, Denecker, Geertrui, Lievens, Sam, Bracke, Marc, Tavernier, Jan, Declercq, Wim, Gevaert, Kris, Berghe, Wim Vanden, Haegeman, Guy, De Bosscher, Karolien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3728325/
https://www.ncbi.nlm.nih.gov/pubmed/23935933
http://dx.doi.org/10.1371/journal.pone.0069115

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3728325/
https://www.ncbi.nlm.nih.gov/pubmed/23935933
http://dx.doi.org/10.1371/journal.pone.0069115

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