Intelligently Targeted Drug Delivery and Enhanced Antitumor Effect by Gelatinase-Responsive Nanoparticles

AIMS: The matrix metalloproteinase (MMP) 2/9, also known as collagenases IV and gelatinases A/B, play a key role in cancer invasion and metastasis. However, the clinical trials of the MMP inhibitors (MMPIs) ended up with disappointing results. In this paper, we synthesized a gelatinase-responsive co...

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Detalles Bibliográficos
Autores principales: Li, Rutian, Wu, Wei, Liu, Qin, Wu, Puyuan, Xie, Li, Zhu, Zhenshu, Yang, Mi, Qian, Xiaoping, Ding, Yin, Yu, Lixia, Jiang, Xiqun, Guan, Wenxian, Liu, Baorui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3728361/
https://www.ncbi.nlm.nih.gov/pubmed/23936062
http://dx.doi.org/10.1371/journal.pone.0069643

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3728361/
https://www.ncbi.nlm.nih.gov/pubmed/23936062
http://dx.doi.org/10.1371/journal.pone.0069643

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