Structure-Based Mechanism for Early PLP-Mediated Steps of Rabbit Cytosolic Serine Hydroxymethyltransferase Reaction

Serine hydroxymethyltransferase catalyzes the reversible interconversion of L-serine and glycine with transfer of one-carbon groups to and from tetrahydrofolate. Active site residue Thr254 is known to be involved in the transaldimination reaction, a crucial step in the catalytic mechanism of all pyr...

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Detalles Bibliográficos
Autores principales: Di Salvo, Martino L., Scarsdale, J. Neel, Kazanina, Galina, Contestabile, Roberto, Schirch, Verne, Wright, H. Tonie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3728543/
https://www.ncbi.nlm.nih.gov/pubmed/23956983
http://dx.doi.org/10.1155/2013/458571

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3728543/
https://www.ncbi.nlm.nih.gov/pubmed/23956983
http://dx.doi.org/10.1155/2013/458571

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