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Structure-Based Mechanism for Early PLP-Mediated Steps of Rabbit Cytosolic Serine Hydroxymethyltransferase Reaction

Serine hydroxymethyltransferase catalyzes the reversible interconversion of L-serine and glycine with transfer of one-carbon groups to and from tetrahydrofolate. Active site residue Thr254 is known to be involved in the transaldimination reaction, a crucial step in the catalytic mechanism of all pyr...

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Detalles Bibliográficos
Autores principales:	Di Salvo, Martino L., Scarsdale, J. Neel, Kazanina, Galina, Contestabile, Roberto, Schirch, Verne, Wright, H. Tonie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3728543/ https://www.ncbi.nlm.nih.gov/pubmed/23956983 http://dx.doi.org/10.1155/2013/458571

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